- Custom synthesis of reagents for research and development projects (e.g. from patents or publications)
- Custom synthesis of reference compounds (including first-time synthesis, with no available procedures/exploratory)
- Custom synthesis of labelled compounds
- Creating API impurities to serve as reference substances in ensuing analyses
- Working on new synthetic techniques, which are replacing time-consuming and expensive extraction methods
- Syntheses that are being redesigned and scaled up to avoid chromatographic purification
- Supplying small amounts of unique, highly pure specialized chemicals on a regular basis in accordance with your non-GMP and GMP needs
Scale up Chemistry Services
Chemveda’s methods and technologies for scale-up synthesis include:
Heterocyclic Chemistry
Organometallic Chemistry
Nucleoside Monomers and Nucleotides
ADC Linkers and Spacers
Building Blocks for Oligonucleotide Synthesis
Peptides
Lipids and Phospholipids
Fluorescent Dye Molecules
Unnatural Amino Acids using Electro Flow Chemistry
Synthesis, Separation of Stereoisomers and Enantiomers
Pheromones
Carbohydrate Chemistry
High-Pressure Reactions
Asymmetric Synthesis
We specialize in efficient scale-up chemistry tailored to your evolving needs. Our infrastructure supports transitions from milligram to multi-kilogram deliveries, utilizing reactors ranging from 500 mL to 200 L (AGLR’s) All Glass Line Reactors. Whether it is the initial synthesis of complex, commercially unavailable molecules, or rapid scale-up for advanced intermediates, our cross-functional collaboration between Discovery Chemistry, Custom Synthesis, and Process R&D ensures consistency, speed, and the quality. This model supports seamless handoffs to PRD, enabling reliable supply chains and accelerated product development for our partners across academia, biotech, pharma and other life sciences sectors.
Our Scale-up Chemistry Team is ready to help you with:
Integrated Team
and Infrastructure
and Infrastructure
We operate through a collaborative, cross-functional model – Discovery Chemistry, Custom Synthesis, and Process R&D teams work in tandem to accelerate knowledge transfer and ensure consistency in scale-up. Internally standardized procedures guide the seamless transition of molecules from initial synthesis to kilo-scale production.
Our dedicated kilo-lab infrastructure supports the rapid, reliable supply of advanced intermediates and custom compounds.
Designed for Speed and Scale
Our Scale-up Chemistry group is built around speed, scalability, and flexibility:
Speedy Delivery
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- Leveraging Discovery ROS to deliver up to multi kg outputs efficiently
- Minimal (or no) process development ensures faster turnaround for time-sensitive projects, including New Chemical Entities (NCEs), advanced intermediates (Int’s), Building Blocks (BB’s), Key Raw Materials (KRM’s), and Key Starting Materials (KSM’s) and helps to overcome supply chain challenges for expensive or scarce materials
- Supplying high-demand molecules
Cost-Effective Solutions
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- From grams to multi kg quantities, we provide cost-effective solutions to meet your requirements
- Approaching syntheses with scalability in mind by using fit-for-scale-up isolation/purification techniques
LET’S COLLABORATE Accelerating Chemistry
Breakthroughs
Breakthroughs